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Uncoupling interferons and the interferon signature explain clinical and transcriptional subsets in SLE

Interferons (IFN) are thought to be key players in systemic lupus erythematosus (SLE). The unique and interactive roles of the different IFN families in SLE pathogenesis, however, remain poorly understood. Using reporter cells engineered to precisely quantify IFN-I, IFN-II and IFN-III activity level...

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Detalles Bibliográficos
Autores principales: Gómez-Bañuelos, Eduardo, Goldman, Daniel W., Andrade, Victoria, Darrah, Erika, Petri, Michelle, Andrade, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491366/
https://www.ncbi.nlm.nih.gov/pubmed/37693590
http://dx.doi.org/10.1101/2023.08.28.23294734