Cargando…
Uncoupling interferons and the interferon signature explain clinical and transcriptional subsets in SLE
Interferons (IFN) are thought to be key players in systemic lupus erythematosus (SLE). The unique and interactive roles of the different IFN families in SLE pathogenesis, however, remain poorly understood. Using reporter cells engineered to precisely quantify IFN-I, IFN-II and IFN-III activity level...
Autores principales: | Gómez-Bañuelos, Eduardo, Goldman, Daniel W., Andrade, Victoria, Darrah, Erika, Petri, Michelle, Andrade, Felipe |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491366/ https://www.ncbi.nlm.nih.gov/pubmed/37693590 http://dx.doi.org/10.1101/2023.08.28.23294734 |
Ejemplares similares
-
Leucocyte subset-specific type 1 interferon signatures in SLE and other immune-mediated diseases
por: Flint, Shaun M, et al.
Publicado: (2016) -
Rheumatoid Arthritis-Associated Mechanisms of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans
por: Gómez-Bañuelos, Eduardo, et al.
Publicado: (2019) -
Alternative exon usage in TRIM21 determines the antigenicity of Ro52/TRIM21 in systemic lupus erythematosus
por: Gomez-Bañuelos, Eduardo, et al.
Publicado: (2022) -
SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature
por: Becker, Amy M., et al.
Publicado: (2013) -
Interferon Genes Are Influenced by 17β-Estradiol in SLE
por: Singh, Ram P., et al.
Publicado: (2021)