Severe preeclampsia is not associated with significant DNA methylation changes but cell proportion changes in the cord blood - caution on the importance of confounding adjustment

Epigenome-wide DNA methylation analysis (EWAS) is an important approach to identify biomarkers for early disease detection and prognosis prediction, yet its results could be confounded by other factors such as cell-type heterogeneity and patient characteristics. In this study, we address the importa...

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Detalles Bibliográficos
Autores principales: Liu, Wenting, Yang, Xiaotong, Mao, Zhixin, Du, Yuheng, Lassiter, Cameron, AlAkwaa, Fadhl M., Benny, Paula A, Garmire, Lana X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491383/
https://www.ncbi.nlm.nih.gov/pubmed/37693517
http://dx.doi.org/10.1101/2023.08.31.23294898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491383/
https://www.ncbi.nlm.nih.gov/pubmed/37693517
http://dx.doi.org/10.1101/2023.08.31.23294898

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