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Kar4 is required for the normal pattern of meiotic gene expression

Kar4p, the yeast homolog of the mammalian methyltransferase subunit METTL14, is required for efficient mRNA m(6)A methylation, which regulates meiotic entry. Kar4p is also required for a second seemingly non-catalytic function during meiosis. Overexpression of the early meiotic transcription factor,...

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Detalles Bibliográficos
Autores principales: Park, Zachory M., Remillard, Matthew, Belnap, Ethan, Rose, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491391/
https://www.ncbi.nlm.nih.gov/pubmed/37639444
http://dx.doi.org/10.1371/journal.pgen.1010898