Cargando…

Myc-regulated miRNAs modulate p53 expression and impact animal survival under nutrient deprivation

The conserved transcription factor Myc regulates cell growth, proliferation and apoptosis, and its deregulation has been associated with human pathologies. Although specific miRNAs have been identified as fundamental components of the Myc tumorigenic program, how Myc regulates miRNA biogenesis remai...

Descripción completa

Detalles Bibliográficos
Autores principales: Gervé, María P., Sánchez, Juan A., Ingaramo, María C., Dekanty, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491395/
https://www.ncbi.nlm.nih.gov/pubmed/37639481
http://dx.doi.org/10.1371/journal.pgen.1010721