SPOP targets the immune transcription factor IRF1 for proteasomal degradation

Adaptation of the functional proteome is essential to counter pathogens during infection, yet precisely timed degradation of these response proteins after pathogen clearance is likewise key to preventing autoimmunity. Interferon regulatory factor 1 (IRF1) plays an essential role as a transcription f...

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Detalles Bibliográficos
Autores principales: Schwartz, Irene, Vunjak, Milica, Budroni, Valentina, Cantoran García, Adriana, Mastrovito, Marialaura, Soderholm, Adrian, Hinterndorfer, Matthias, de Almeida, Melanie, Hacker, Kathrin, Wang, Jingkui, Froussios, Kimon, Jude, Julian, Decker, Thomas, Zuber, Johannes, Versteeg, Gijs A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491434/
https://www.ncbi.nlm.nih.gov/pubmed/37622993
http://dx.doi.org/10.7554/eLife.89951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491434/
https://www.ncbi.nlm.nih.gov/pubmed/37622993
http://dx.doi.org/10.7554/eLife.89951

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