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Clinical Value of Longitudinal Serum Neurofilament Light Chain in Prodromal Genetic Frontotemporal Dementia

BACKGROUND AND OBJECTIVES: Elevated serum neurofilament light chain (NfL) is used to identify carriers of genetic frontotemporal dementia (FTD) pathogenic variants approaching prodromal conversion. Yet, the magnitude and timeline of NfL increase are still unclear. Here, we investigated the predictiv...

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Detalles Bibliográficos
Autores principales: Giannini, Lucia A.A., Seelaar, Harro, van der Ende, Emma L., Poos, Jackie M., Jiskoot, Lize C., Dopper, Elise G.P., Pijnenburg, Yolande A.L., Willemse, Eline A.J., Vermunt, Lisa, Teunissen, Charlotte E., van Swieten, John C., Meeter, Lieke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491440/
https://www.ncbi.nlm.nih.gov/pubmed/37491327
http://dx.doi.org/10.1212/WNL.0000000000207581