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3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells

Mechanical stimuli from the extracellular environment affect cell morphology and functionality. Recently, we reported that mesenchymal stem cells (MSCs) grown in a custom-made 3D microscaffold, the Nichoid, are able to express higher levels of stemness markers. In fact, the Nichoid is an interesting...

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Detalles Bibliográficos
Autores principales: Donnaloja, Francesca, Raimondi, Manuela Teresa, Messa, Letizia, Barzaghini, Bianca, Carnevali, Federica, Colombo, Emanuele, Mazza, Davide, Martinelli, Chiara, Boeri, Lucia, Rey, Federica, Cereda, Cristina, Osellame, Roberto, Cerullo, Giulio, Carelli, Stephana, Soncini, Monica, Jacchetti, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491463/
https://www.ncbi.nlm.nih.gov/pubmed/37692376
http://dx.doi.org/10.1063/5.0153215