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Commonalities and differences in the mutational signature and somatic driver mutation landscape across solid and hollow viscus organs
Advances in sequencing have revealed a highly variegated landscape of mutational signatures and somatic driver mutations in a range of normal tissues. Normal tissues accumulate mutations at varying rates ranging from 11 per cell per year in the liver, to 1879 per cell per year in the bladder. In add...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491491/ https://www.ncbi.nlm.nih.gov/pubmed/37573406 http://dx.doi.org/10.1038/s41388-023-02802-7 |