FANCA deficiency promotes leukaemic progression by allowing the emergence of cells carrying oncogenic driver mutations

Leukaemia is caused by the clonal evolution of a cell that accumulates mutations/genomic rearrangements, allowing unrestrained cell growth. However, recent identification of leukaemic mutations in the blood cells of healthy individuals revealed that additional events are required to expand the mutat...

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Detalles Bibliográficos
Autores principales: Pawlikowska, Patrycja, Delestré, Laure, Gregoricchio, Sebastian, Oppezzo, Alessia, Esposito, Michela, Diop, M’ Boyba, Rosselli, Filippo, Guillouf, Christel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491493/
https://www.ncbi.nlm.nih.gov/pubmed/37573408
http://dx.doi.org/10.1038/s41388-023-02800-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491493/
https://www.ncbi.nlm.nih.gov/pubmed/37573408
http://dx.doi.org/10.1038/s41388-023-02800-9

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