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FANCA deficiency promotes leukaemic progression by allowing the emergence of cells carrying oncogenic driver mutations
Leukaemia is caused by the clonal evolution of a cell that accumulates mutations/genomic rearrangements, allowing unrestrained cell growth. However, recent identification of leukaemic mutations in the blood cells of healthy individuals revealed that additional events are required to expand the mutat...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491493/ https://www.ncbi.nlm.nih.gov/pubmed/37573408 http://dx.doi.org/10.1038/s41388-023-02800-9 |