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Structural convergence endows nuclear transport receptor Kap114p with a transcriptional repressor function toward TATA-binding protein

The transcription factor TATA-box binding protein (TBP) modulates gene expression in nuclei. This process requires the involvement of nuclear transport receptors, collectively termed karyopherin-β (Kap-β) in yeast, and various regulatory factors. In previous studies we showed that Kap114p, a Kap-β t...

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Detalles Bibliográficos
Autores principales: Liao, Chung-Chi, Wang, Yi-Sen, Pi, Wen-Chieh, Wang, Chun-Hsiung, Wu, Yi-Min, Chen, Wei-Yi, Hsia, Kuo-Chiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491584/
https://www.ncbi.nlm.nih.gov/pubmed/37684250
http://dx.doi.org/10.1038/s41467-023-41206-9