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Structural variation of the coding and non-coding human pharmacogenome

Genetic variants in drug targets and genes encoding factors involved in drug absorption, distribution, metabolism and excretion (ADME) can have pronounced impacts on drug pharmacokinetics, response, and toxicity. While the landscape of genetic variability at the level of single nucleotide variants (...

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Detalles Bibliográficos
Autores principales: Tremmel, Roman, Zhou, Yitian, Schwab, Matthias, Lauschke, Volker M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491600/
https://www.ncbi.nlm.nih.gov/pubmed/37684227
http://dx.doi.org/10.1038/s41525-023-00371-y