Phase separation of protein mixtures is driven by the interplay of homotypic and heterotypic interactions

Prion-like low-complexity domains (PLCDs) are involved in the formation and regulation of distinct biomolecular condensates that form via phase separation coupled to percolation. Intracellular condensates often encompass numerous distinct proteins with PLCDs. Here, we combine simulations and experim...

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Detalles Bibliográficos
Autores principales: Farag, Mina, Borcherds, Wade M., Bremer, Anne, Mittag, Tanja, Pappu, Rohit V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491635/
https://www.ncbi.nlm.nih.gov/pubmed/37684240
http://dx.doi.org/10.1038/s41467-023-41274-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491635/
https://www.ncbi.nlm.nih.gov/pubmed/37684240
http://dx.doi.org/10.1038/s41467-023-41274-x

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