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CD44 connects autophagy decline and ageing in the vascular endothelium

The decline of endothelial autophagy is closely related to vascular senescence and disease, although the molecular mechanisms connecting these outcomes in vascular endothelial cells (VECs) remain unclear. Here, we identify a crucial role for CD44, a multifunctional adhesion molecule, in controlling...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Yang, Peichang, Chen, Jingxuan, Chen, Zhiqiang, Liu, Zhihui, Feng, Gaoqing, Sha, Fangfang, Li, Zirui, Xu, Zaoyi, Huang, Yating, Shi, Xiaotong, Li, Xuebiao, Cui, Jiatian, Zhang, Chenyi, Fan, Pei, Cui, Liuqing, Shen, Yunpeng, Zhou, Guangzhou, Jing, Hongjuan, Ma, Shiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491636/
https://www.ncbi.nlm.nih.gov/pubmed/37684253
http://dx.doi.org/10.1038/s41467-023-41346-y