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Structural and functional analyses of Burkholderia pseudomallei BPSL1038 reveal a Cas-2/VapD nuclease sub-family

Burkholderia pseudomallei is a highly versatile pathogen with ~25% of its genome annotated to encode hypothetical proteins. One such hypothetical protein, BPSL1038, is conserved across seven bacterial genera and 654 Burkholderia spp. Here, we present a 1.55 Å resolution crystal structure of BPSL1038...

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Detalles Bibliográficos
Autores principales: Shaibullah, Sofiyah, Shuhaimi, Nurshahirah, Ker, De-Sheng, Mohd-Sharif, Nurhikmah, Ho, Kok Lian, Teh, Aik-Hong, Waterman, Jitka, Tang, Thean-Hock, Wong, Rui-Rui, Nathan, Sheila, Mohamed, Rahmah, Ng, Min Jia, Fung, Shin-Yee, Jonet, Mohd Anuar, Firdaus-Raih, Mohd, Ng, Chyan Leong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491678/
https://www.ncbi.nlm.nih.gov/pubmed/37684342
http://dx.doi.org/10.1038/s42003-023-05265-4