Deciphering complex breakage-fusion-bridge genome rearrangements with Ambigram

Breakage-fusion-bridge (BFB) is a complex rearrangement that leads to tumor malignancy. Existing models for detecting BFBs rely on the ideal BFB hypothesis, ruling out the possibility of BFBs entangled with other structural variations, that is, complex BFBs. We propose an algorithm Ambigram to ident...

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Detalles Bibliográficos
Autores principales: Li, Chaohui, Chen, Lingxi, Pan, Guangze, Zhang, Wenqian, Li, Shuai Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491683/
https://www.ncbi.nlm.nih.gov/pubmed/37684230
http://dx.doi.org/10.1038/s41467-023-41259-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491683/
https://www.ncbi.nlm.nih.gov/pubmed/37684230
http://dx.doi.org/10.1038/s41467-023-41259-w

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