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Blockade of tumor-derived colony-stimulating factor 1 (CSF1) promotes an immune-permissive tumor microenvironment

The macrophage colony-stimulating factor 1 (CSF1) is a chemokine essential for the survival, proliferation, and differentiation of mononuclear phagocytes from hemopoietic stem cells. In addition to its essential physiological role in normal tissues, the CSF1/CSF1 receptor axis is known to be overexp...

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Detalles Bibliográficos
Autores principales: Maldonado, Maria del Mar, Schlom, Jeffrey, Hamilton, Duane H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491706/
https://www.ncbi.nlm.nih.gov/pubmed/37505292
http://dx.doi.org/10.1007/s00262-023-03496-2