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Zika virus targets human trophoblast stem cells and prevents syncytialization in placental trophoblast organoids

Zika virus (ZIKV) infection during pregnancy threatens pregnancy and fetal health. However, the infectivity and pathological effects of ZIKV on placental trophoblast progenitor cells in early human embryos remain largely unknown. Here, using human trophoblast stem cells (hTSCs), we demonstrated that...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Huang, Xing-Yao, Sun, Meng-Xu, Wang, Yue, Zhou, Hang-Yu, Tian, Ying, He, Beijia, Li, Kai, Li, De-Yu, Wu, Ai-Ping, Wang, Hongmei, Qin, Cheng-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491779/
https://www.ncbi.nlm.nih.gov/pubmed/37684223
http://dx.doi.org/10.1038/s41467-023-41158-0