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Structures of liganded glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis
Many eukaryotic receptors and enzymes rely on glycosylphosphatidylinositol (GPI) anchors for membrane localization and function. The transmembrane complex GPI-T recognizes diverse proproteins at a signal peptide region that lacks consensus sequence and replaces it with GPI via a transamidation react...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491789/ https://www.ncbi.nlm.nih.gov/pubmed/37684232 http://dx.doi.org/10.1038/s41467-023-41281-y |