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Oxidative stress mediates the inhibitory effects of Manzamine A on uterine leiomyoma cell proliferation and extracellular matrix deposition via SOAT inhibition

Uterine fibroids, the most common benign tumors of the myometrium in women, are characterized by abnormal extracellular matrix deposition and uterine smooth muscle cell neoplasia, with high recurrence rates. Here, we investigated the potential of the marine natural product manzamine A (Manz A), whic...

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Detalles Bibliográficos
Autores principales: Lin, Li-Chun, Chang, Hsin-Yi, Kuo, Tzu-Ting, Chen, Hsin-Yuan, Liu, Wen-Shan, Lo, Yii-Jwu, Hsia, Shih-Min, Huang, Tsui-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491796/
https://www.ncbi.nlm.nih.gov/pubmed/37666118
http://dx.doi.org/10.1016/j.redox.2023.102861