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Oxidative stress mediates the inhibitory effects of Manzamine A on uterine leiomyoma cell proliferation and extracellular matrix deposition via SOAT inhibition
Uterine fibroids, the most common benign tumors of the myometrium in women, are characterized by abnormal extracellular matrix deposition and uterine smooth muscle cell neoplasia, with high recurrence rates. Here, we investigated the potential of the marine natural product manzamine A (Manz A), whic...
Autores principales: | Lin, Li-Chun, Chang, Hsin-Yi, Kuo, Tzu-Ting, Chen, Hsin-Yuan, Liu, Wen-Shan, Lo, Yii-Jwu, Hsia, Shih-Min, Huang, Tsui-Chin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491796/ https://www.ncbi.nlm.nih.gov/pubmed/37666118 http://dx.doi.org/10.1016/j.redox.2023.102861 |
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