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Structural dynamics influences the antibacterial activity of a cell-penetrating peptide (KFF)(3)K
Given the widespread demand for novel antibacterial agents, we modified a cell-penetrating peptide (KFF)(3)K to transform it into an antibacterial peptide. Namely, we inserted a hydrocarbon staple into the (KFF)(3)K sequence to induce and stabilize its membrane-active secondary structure. The staple...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491836/ https://www.ncbi.nlm.nih.gov/pubmed/37684254 http://dx.doi.org/10.1038/s41598-023-38745-y |