Cargando…

Protocol to visualize the distribution of exogenously administered small molecules in the mouse brain

Here, we present fixation-driven chemical crosslinking of exogenous ligands, a protocol to visualize the distribution of exogenously administered small molecules in the mouse brain. We first describe the probe design of the small molecules of interest and the probe microinjection into a live mouse b...

Descripción completa

Detalles Bibliográficos
Autores principales: Mino, Takeharu, Nonaka, Hiroshi, Sakamoto, Seiji, Oh, Jae Hoon, Hamachi, Itaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491850/
https://www.ncbi.nlm.nih.gov/pubmed/37660299
http://dx.doi.org/10.1016/j.xpro.2023.102555