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Protocol to study projection-specific circuits in the basal ganglia of adult mice using viral vector tracing, optogenetics, and patch-clamp technique

Analysis of synaptic strength and plasticity provides functional insights of complicated neural circuits. Here, we describe steps for cell- and projection-specific optogenetic manipulation of divergent basal ganglia circuits using anterograde and retrograde viral vectors. We quantitatively analyze s...

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Detalles Bibliográficos
Autores principales: Ji, Ya-Wei, Xu, Xiang-Ying, Yin, Cui, Zhou, Chunyi, Xiao, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491855/
https://www.ncbi.nlm.nih.gov/pubmed/37660296
http://dx.doi.org/10.1016/j.xpro.2023.102551