Cellular senescence-driven transcriptional reprogramming of the MAFB/NOTCH3 axis activates the PI3K/AKT pathway and promotes osteosarcoma progression

Osteosarcoma is the most common primary malignancy of bones and primarily occurs in adolescents and young adults. However, a second smaller peak of osteosarcoma incidence was reported in the elderly aged more than 60. Elderly patients with osteosarcoma exhibit different characteristics compared to y...

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Detalles Bibliográficos
Autores principales: Zhang, Zhenhao, Jing, Doudou, Xuan, Baijun, Zhang, Zhicai, Wu, Wei, Shao, Zengwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491868/
https://www.ncbi.nlm.nih.gov/pubmed/37692492
http://dx.doi.org/10.1016/j.gendis.2023.02.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491868/
https://www.ncbi.nlm.nih.gov/pubmed/37692492
http://dx.doi.org/10.1016/j.gendis.2023.02.028

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