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The emerging roles of lysine-specific demethylase 4A in cancer: Implications in tumorigenesis and therapeutic opportunities

Lysine-specific demethylase 4 A (KDM4A, also named JMJD2A, KIA0677, or JHDM3A) is a demethylase that can remove methyl groups from histones H3K9me2/3, H3K36me2/3, and H1.4K26me2/me3. Accumulating evidence suggests that KDM4A is not only involved in body homeostasis (such as cell proliferation, migra...

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Detalles Bibliográficos
Autores principales: Yang, Guanjun, Li, Changyun, Tao, Fan, Liu, Yanjun, Zhu, Minghui, Du, Yu, Fei, Chenjie, She, Qiusheng, Chen, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491877/
https://www.ncbi.nlm.nih.gov/pubmed/37692513
http://dx.doi.org/10.1016/j.gendis.2022.12.020