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The m(6)A regulator KIAA1429 stabilizes RAB27B mRNA and promotes the progression of chronic myeloid leukemia and resistance to targeted therapy

Chronic myeloid leukemia (CML) is a common adult leukemia. Both the acute phase of the disease and the adverse effects of anti-cancer treatments can lead to a poor prognosis. The N(6)-methyladenine (m(6)A) modification plays an important regulatory role in various physiological and pathological proc...

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Detalles Bibliográficos
Autores principales: Yao, Fangyi, Zhong, Fangmin, Jiang, Junyao, Cheng, Ying, Xu, Shuai, Liu, Jing, Lin, Jin, Zhang, Jing, Li, Shuqi, Li, Meiyong, Xu, Yanmei, Huang, Bo, Wang, Xiaozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491918/
https://www.ncbi.nlm.nih.gov/pubmed/37692484
http://dx.doi.org/10.1016/j.gendis.2023.03.016