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WNT/β-catenin signaling in hepatocellular carcinoma: The aberrant activation, pathogenic roles, and therapeutic opportunities
Hepatocellular carcinoma (HCC) is a liver cancer, highly heterogeneous both at the histopathological and molecular levels. It arises from hepatocytes as the result of the accumulation of numerous genomic alterations in various signaling pathways, including canonical WNT/β-catenin, AKT/mTOR, MAPK pat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491942/ https://www.ncbi.nlm.nih.gov/pubmed/37692481 http://dx.doi.org/10.1016/j.gendis.2023.02.050 |