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WNT/β-catenin signaling in hepatocellular carcinoma: The aberrant activation, pathogenic roles, and therapeutic opportunities

Hepatocellular carcinoma (HCC) is a liver cancer, highly heterogeneous both at the histopathological and molecular levels. It arises from hepatocytes as the result of the accumulation of numerous genomic alterations in various signaling pathways, including canonical WNT/β-catenin, AKT/mTOR, MAPK pat...

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Detalles Bibliográficos
Autores principales: Gajos-Michniewicz, Anna, Czyz, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491942/
https://www.ncbi.nlm.nih.gov/pubmed/37692481
http://dx.doi.org/10.1016/j.gendis.2023.02.050