Targeting ARF1-IQGAP1 interaction to suppress colorectal cancer metastasis and vemurafenib resistance

INTRODUCTION: Acquired resistance to BRAF inhibitor vemurafenib is frequently observed in metastatic colorectal cancer (CRC), and it is a thorny issue that results in treatment failure. As adaptive responses for vemurafenib treatment, a series of cellular bypasses are response for the adaptive feedb...

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Detalles Bibliográficos
Autores principales: Hu, Hui-Fang, Gao, Gui-Bin, He, Xuan, Li, Yu-Ying, Li, Yang-Jia, Li, Bin, Pan, YunLong, Wang, Yang, He, Qing-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491971/
https://www.ncbi.nlm.nih.gov/pubmed/36396045
http://dx.doi.org/10.1016/j.jare.2022.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491971/
https://www.ncbi.nlm.nih.gov/pubmed/36396045
http://dx.doi.org/10.1016/j.jare.2022.11.006

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