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Targeting ARF1-IQGAP1 interaction to suppress colorectal cancer metastasis and vemurafenib resistance
INTRODUCTION: Acquired resistance to BRAF inhibitor vemurafenib is frequently observed in metastatic colorectal cancer (CRC), and it is a thorny issue that results in treatment failure. As adaptive responses for vemurafenib treatment, a series of cellular bypasses are response for the adaptive feedb...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491971/ https://www.ncbi.nlm.nih.gov/pubmed/36396045 http://dx.doi.org/10.1016/j.jare.2022.11.006 |