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IGF2BPs as novel m(6)A readers: Diverse roles in regulating cancer cell biological functions, hypoxia adaptation, metabolism, and immunosuppressive tumor microenvironment

m(6)A methylation is the most frequent modification of mRNA in eukaryotes and plays a crucial role in cancer progression by regulating biological functions. Insulin-like growth factor 2 mRNA-binding proteins (IGF2BP) are newly identified m(6)A ‘readers’. They belong to a family of RNA-binding protei...

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Detalles Bibliográficos
Autores principales: Duan, Meiqi, Liu, Haiyang, Xu, Shasha, Yang, Zhi, Zhang, Fusheng, Wang, Guang, Wang, Yutian, Zhao, Shan, Jiang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491980/
https://www.ncbi.nlm.nih.gov/pubmed/37692485
http://dx.doi.org/10.1016/j.gendis.2023.06.017