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Post-embryonic endogenous expression and localization of LET-60/Ras in C. elegans

Ras GTPases regulate many developmental and physiological processes and mutations in Ras are associated with numerous human cancers. Here, we report the function, levels, and localization of an N-terminal knock-in of mNeonGreen (mNG) into C. elegans LET-60 /Ras. mNG:: LET-60 interferes with some but...

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Detalles Bibliográficos
Autores principales: Jayadev, Ranjay, Chi, Qiuyi, Sherwood, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492041/
https://www.ncbi.nlm.nih.gov/pubmed/37692087
http://dx.doi.org/10.17912/micropub.biology.000931