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Gut bacteria induce IgA expression in pituitary hormone-secreting cells during aging

Pituitary hormone decline is a hallmark of aging. However, the precise gene regulation mechanism during pituitary aging is unclear. Here, we characterized the cell population alteration and global transcriptional change during pituitary aging through single-cell RNA sequencing (scRNA-seq). We found...

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Detalles Bibliográficos
Autores principales: Li, Yehua, Wang, Jiawen, Wang, Rui, Chang, Ying, Wang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492204/
https://www.ncbi.nlm.nih.gov/pubmed/37692284
http://dx.doi.org/10.1016/j.isci.2023.107747