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LAT1 (SLC7A5) catalyzes copper(histidinate) transport switching from antiport to uniport mechanism

LAT1 (SLC7A5) is one of the most studied membrane transporters due to its relevance to physiology in supplying essential amino acids to brain and fetus, and to pathology being linked to nervous or embryo alterations; moreover, LAT1 over-expression is always associated with cancer development. Thus,...

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Detalles Bibliográficos
Autores principales: Scanga, Raffaella, Scalise, Mariafrancesca, Marino, Nadia, Parisi, Francesco, Barca, Donatella, Galluccio, Michele, Brunocilla, Chiara, Console, Lara, Indiveri, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492218/
https://www.ncbi.nlm.nih.gov/pubmed/37692288
http://dx.doi.org/10.1016/j.isci.2023.107738