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Echinococcus granulosus cyst fluid inhibits inflammatory responses through inducing histone demethylase KDM5B in macrophages

BACKGROUND: Echinococcus granulosus cyst fluid (EgCF) weakens macrophage inflammatory responses, thereby enabling the parasite to evade the immune system. However, the role of histone modification in this process remains to be explored. METHODS: The levels of IL-6, TNF-α, IL-10, H3K4me3, and KDM5B w...

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Detalles Bibliográficos
Autores principales: Wang, Xiaopeng, Lin, Ruolin, Fu, Chunxue, Yang, Chun, Dong, Dan, Wu, Xiangwei, Chen, Xueling, Wang, Lianghai, Hou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492338/
https://www.ncbi.nlm.nih.gov/pubmed/37689671
http://dx.doi.org/10.1186/s13071-023-05948-1