The Effect of Simulated Patient Death on Learner’s Stress and Knowledge Retention: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Making the simulated patient die is one of the controversial decisions in healthcare simulation. Some experts believe that we should never make the manikin die as they believe the facilitator is deceiving the learners, whereas other groups of experts believe that there are advantages in making the simulated patient die as it provides a valuable learning experience to the learners, and it is as close to reality as possible. Hence, we undertook this review to know whether simulated patient mortality benefits the learners. A systematic literature search was performed in Embase, Scopus, PubMed Central, CENTRAL, MEDLINE, and Google Scholar. Randomized controlled trials assessing the learner’s stress and knowledge retention when the simulated patient dies were eligible for inclusion. Comparative intervention effect estimates obtained from meta-analyses were represented as pooled standardized mean difference (SMD) with a 95% CI. Six studies with 384 participants (learners) were eligible for the analysis. All the studies had some concerns when the risk of bias was assessed. In the simulated patient mortality group, the learners experienced higher stress as assessed compared to the group where the simulated patient survives. The two groups' pooled mean difference for anxiety and stress levels was 0.63 (0.17-1.09). Three out of five studies showed improved knowledge retention in the simulated mortality group, one showed no difference, and one showed decreased knowledge retention in the simulated mortality group. The stress response of learners when exposed to simulated mortality during a simulation session is higher than the simulated survival group. However, this increased stress response is processed by the students differently. Some students will thrive when increased stress is presented to them, while some students perceive it negatively. Thus, this increased stress response can lead to knowledge retention if the timing of the stress response happens mainly during debriefing for select students. The role of the facilitator is also important as skilled debriefers will be able to use this increased stress to their advantage to increase knowledge retention. Thus, simulated mortality can be used as an effective stressor for increasing knowledge retention during the debriefing phase for select students by a skilled debriefer. This study would aid the simulation policymakers, simulation faculties, and simulation researchers in the impact of simulated patient death and learners’ stress response. If the simulation scenario is designed well with robust pre-briefing, this increased stress response can enhance learning and knowledge retention during debriefing.