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Identification of sodium channel toxins from marine cone snails of the subgenera Textilia and Afonsoconus

Voltage-gated sodium (Na(V)) channels are transmembrane proteins that play a critical role in electrical signaling in the nervous system and other excitable tissues. µ-Conotoxins are peptide toxins from the venoms of marine cone snails (genus Conus) that block Na(V) channels with nanomolar potency....

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Detalles Bibliográficos
Autores principales: McMahon, Kirsten L., O’Brien, Henrik, Schroeder, Christina I., Deuis, Jennifer R., Venkatachalam, Dhananjeyan, Huang, Di, Green, Brad R., Bandyopadhyay, Pradip K., Li, Qing, Yandell, Mark, Safavi-Hemami, Helena, Olivera, Baldomero M., Vetter, Irina, Robinson, Samuel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492761/
https://www.ncbi.nlm.nih.gov/pubmed/37689602
http://dx.doi.org/10.1007/s00018-023-04935-0