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Identification of sodium channel toxins from marine cone snails of the subgenera Textilia and Afonsoconus
Voltage-gated sodium (Na(V)) channels are transmembrane proteins that play a critical role in electrical signaling in the nervous system and other excitable tissues. µ-Conotoxins are peptide toxins from the venoms of marine cone snails (genus Conus) that block Na(V) channels with nanomolar potency....
Autores principales: | McMahon, Kirsten L., O’Brien, Henrik, Schroeder, Christina I., Deuis, Jennifer R., Venkatachalam, Dhananjeyan, Huang, Di, Green, Brad R., Bandyopadhyay, Pradip K., Li, Qing, Yandell, Mark, Safavi-Hemami, Helena, Olivera, Baldomero M., Vetter, Irina, Robinson, Samuel D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492761/ https://www.ncbi.nlm.nih.gov/pubmed/37689602 http://dx.doi.org/10.1007/s00018-023-04935-0 |
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