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Exploring the levodopa-paradox of freezing of gait in dopaminergic medication-naïve Parkinson’s disease populations

The relationship between dopaminergic treatment and freezing of gait (FOG) in Parkinson’s disease (PD) is complex: levodopa is the most effective symptomatic treatment for FOG, but long-term pulsatile levodopa treatment has also been linked to an increase in the occurrence of FOG. This concept, howe...

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Detalles Bibliográficos
Autores principales: Jansen, Jamie A. F., Capato, Tamine T. C., Darweesh, Sirwan K. L., Barbosa, Egberto R., Donders, Rogier, Bloem, Bastiaan R., Nonnekes, Jorik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492797/
https://www.ncbi.nlm.nih.gov/pubmed/37689706
http://dx.doi.org/10.1038/s41531-023-00575-0