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PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation

Multiple Sclerosis (MS) is a chronic autoimmune inflammatory disorder of the central nervous system (CNS). Current therapies mainly target inflammatory processes during acute stages, but effective treatments for progressive MS are limited. In this context, astrocytes have gained increasing attention...

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Detalles Bibliográficos
Autores principales: Linnerbauer, Mathias, Beyer, Tobias, Nirschl, Lucy, Farrenkopf, Daniel, Lößlein, Lena, Vandrey, Oliver, Peter, Anne, Tsaktanis, Thanos, Kebir, Hania, Laplaud, David, Oellinger, Rupert, Engleitner, Thomas, Alvarez, Jorge Ivan, Rad, Roland, Korn, Thomas, Hemmer, Bernhard, Quintana, Francisco J., Rothhammer, Veit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492803/
https://www.ncbi.nlm.nih.gov/pubmed/37689786
http://dx.doi.org/10.1038/s41467-023-40982-8