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PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation
Multiple Sclerosis (MS) is a chronic autoimmune inflammatory disorder of the central nervous system (CNS). Current therapies mainly target inflammatory processes during acute stages, but effective treatments for progressive MS are limited. In this context, astrocytes have gained increasing attention...
Autores principales: | Linnerbauer, Mathias, Beyer, Tobias, Nirschl, Lucy, Farrenkopf, Daniel, Lößlein, Lena, Vandrey, Oliver, Peter, Anne, Tsaktanis, Thanos, Kebir, Hania, Laplaud, David, Oellinger, Rupert, Engleitner, Thomas, Alvarez, Jorge Ivan, Rad, Roland, Korn, Thomas, Hemmer, Bernhard, Quintana, Francisco J., Rothhammer, Veit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492803/ https://www.ncbi.nlm.nih.gov/pubmed/37689786 http://dx.doi.org/10.1038/s41467-023-40982-8 |
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