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Impact of fractionated cisplatin and radiation treatment on cell growth and accumulation of DNA damage in two normal cell types differing in origin

Evidence on the impact of chemotherapy on radiotherapy-induced second malignant neoplasms is controversial. We estimated how cisplatin modulates the in vitro response of two normal cell types to fractionated radiation. AHH-1 lymphoblasts and VH10 fibroblasts were irradiated at 1 Gy/fraction 5 and 3...

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Detalles Bibliográficos
Autores principales: Akuwudike, Pamela, López-Riego, Milagrosa, Dehours, Cloé, Lundholm, Lovisa, Wojcik, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492820/
https://www.ncbi.nlm.nih.gov/pubmed/37689722
http://dx.doi.org/10.1038/s41598-023-39409-7