Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lung

Alveolar type 2 (AT2) cells function as stem cells in the adult lung and aid in repair after injury. The current study aimed to understand the signaling events that control differentiation of this therapeutically relevant cell type during human development. Using lung explant and organoid models, we...

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Detalles Bibliográficos
Autores principales: Frum, Tristan, Hsu, Peggy P., Hein, Renee F. C., Conchola, Ansley S., Zhang, Charles J., Utter, Olivia R., Anand, Abhinav, Zhang, Yi, Clark, Sydney G., Glass, Ian, Sexton, Jonathan Z., Spence, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492838/
https://www.ncbi.nlm.nih.gov/pubmed/37689780
http://dx.doi.org/10.1038/s41536-023-00325-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492838/
https://www.ncbi.nlm.nih.gov/pubmed/37689780
http://dx.doi.org/10.1038/s41536-023-00325-z

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