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Epicardial Adipose Tissue–Derived Leptin Promotes Myocardial Injury in Metabolic Syndrome Rats Through PKC/NADPH Oxidase/ROS Pathway

BACKGROUND: The epicardial adipose tissue (EAT) of metabolic syndrome (MetS) is abnormally accumulated with dysfunctional secretion of adipokines, closely relating to cardiac dysfunction. The current study was designed to identify the effects of EAT‐derived leptin on the myocardium of MetS rats and...

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Detalles Bibliográficos
Autores principales: Chen, Hui, Liu, Lei, Li, Min, Zhu, Danjun, Tian, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10492984/
https://www.ncbi.nlm.nih.gov/pubmed/37489731
http://dx.doi.org/10.1161/JAHA.123.029415