Combining Olaparib and Ascorbic Acid on Nanoparticles to Enhance the Drug Toxic Effects in Pancreatic Cancer

INTRODUCTION: Pancreatic cancer (PC) shows a very poor response to current treatments. Development of drug resistance is one of the causes of the therapy failure, being PARP1 (poly ADP-ribose polymerase 1) a relevant protein in the resistance mechanism. In this work, we have functionalized calcium p...

Descripción completa

Detalles Bibliográficos
Autores principales: Quiñonero, Francisco, Parra-Torrejón, Belén, Ramírez-Rodríguez, Gloria B, Garcés, Victor, Delgado-López, José M, Jiménez-Luna, Cristina, Perazzoli, Gloria, Melguizo, Consolación, Prados, Jose, Ortíz, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493099/
https://www.ncbi.nlm.nih.gov/pubmed/37701822
http://dx.doi.org/10.2147/IJN.S415631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493099/
https://www.ncbi.nlm.nih.gov/pubmed/37701822
http://dx.doi.org/10.2147/IJN.S415631

Ejemplares similares