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Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation

Major depressive disorder (MDD) is a pervasive and devastating mental disease. Broad spectrum histone deacetylase (HDAC) inhibitors are considered to have potential for the treatment of depressive phenotype in mice. However, due to its non-specific inhibition, it has extensive side effects and can n...

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Detalles Bibliográficos
Autores principales: Dai, Yunjian, Wei, Taofeng, Huang, Yuwen, Bei, Yun, Lin, Haoran, Shen, Zexu, Yu, Lingyan, Yang, Mingdong, Xu, Huimin, He, Wei, Lin, Zheng, Dai, Haibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493204/
https://www.ncbi.nlm.nih.gov/pubmed/37690046
http://dx.doi.org/10.1007/s00018-023-04945-y