NEK7 inhibition attenuates Aβ(42)-induced cognitive impairment by regulating TLR4/NF-κB and the NLRP3 inflammasome in mice

NEK7 is a serine/threonine kinase that regulates cell mitosis and the activation of the nucleotide-binding oligomerization domain-like (NOD-like) receptor thermal protein domain associated protein 3 (NLRP3) inflammasome, and is related to neuroinflammation and neuronal damage. The purpose of this st...

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Detalles Bibliográficos
Autores principales: Li, Peng, He, Yifan, Yang, Qian, Guo, Hena, Li, Nini, Zhang, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493210/
https://www.ncbi.nlm.nih.gov/pubmed/37700846
http://dx.doi.org/10.3164/jcbn.22-105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493210/
https://www.ncbi.nlm.nih.gov/pubmed/37700846
http://dx.doi.org/10.3164/jcbn.22-105

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