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Knockdown of Secernin 1 inhibit cell invasion and migration by activating the TGF-β/Smad3 pathway in oral squamous cell carcinomas

Secernin-1 (SCRN1) is a regulator of exocytosis in mast cells. Recently, SCRN1 was reported to be correlated with the prognosis of colorectal cancer and gastric cancer, but its functional effects on oral squamous cell carcinoma (OSCC) remain unclear. Our aim was to explore the expression pattern and...

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Detalles Bibliográficos
Autores principales: Xiao, Li, Zhang, Ting, Zheng, Kaiyue, Xiao, Qian, Zhang, Weifang, Zhang, Dandan, Wu, Dengxun, He, Chanjuan, Zhou, Yifei, Liu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493221/
https://www.ncbi.nlm.nih.gov/pubmed/37691034
http://dx.doi.org/10.1038/s41598-023-41504-8